Programme

Agenda of Lisbon Meeting

COST Action no. BM1406

	Wednesday 9^th March
14:00-16:00	Registration

16:00	Welcome address
16:30	Opening Lecture
	Dr. Pierre Martineau (Fr)
	Design and use of antibody libraries for the development of therapeutic antibodies

17:30	Pr. Thomas De Coursey (USA)
	title

18:20	Welcome drink

	Thursday 10^th March 2016

09:00	Lecture 1
	Dr. Catelijne Stortelers, Ablynx (Ge)
	Therapeutic targeting of ion channels with Nanobodies
10:00	Dr. Ettrich R.
	Cation translocation in human ORAI channels: Modeling and simulations.
10:20	Coffee break / posters
10:40	Pinto Espinoza C.
	Nanobodies that antagonize the P2X7 ion channel ameliorate inflammatory diseases
11:00	Dr. Rupprecht A.
	A proton leak during proliferation?
11:20	Dr. Louvet C.
	Exploring the role of Torid cation fluxes in Th17 cells
11:40	Dr. Jawhari A.
	Native and functional isolation of ion channels for therapeutic purposes
12:00	Lunch

14:00	Lecture 2
	Pr. Claude Malvy, Roussy Institute (Fr)
	Therapeutic siRNAs: principle of action and cell delivery by functionalized Nanoparticles.
15:00	Dr. Konu O.
	Identification and validation of the mRNA-miRNA coexpression network obtained from a CHRNA5 RNAi model in MCF7 cells
15:20	Dr. Majewski L.
	Transgenic mice overexpressing key store operated calcium entry proteins in neurons offer novel possibilities for studying calcium signalling in AD

15:40	Coffee break / Poster

16:00	Dr. Rottoli E.
	Signaling and metabolic reprogramming of effector/memory T cells by purinergic P2X7 receptor

16:30	MC Meeting
	H2020

18:30

20:00	Meeting Dinner

	Friday 11^th March 2016

	Lecture 3
09:00	Dr. Jean-François Liégois, Liège (Be)
	Chemical and biological tools to explore SK channel functions and therapeutic potentials
10:00	Dr. Quieroz M.J.
	Synthesis of heterocyclic compounds that may interact with ion channels producing an immune response
10:20	Dr. Martin-Sanchez F
	Novel blockers of P2X7 receptor-induced membrane permeabilization inhibit unconventional IL-1² release
10:40	Coffee break / Poster
11:00	Homerin G.
	"Synthesis of new ligands of the P2X7 receptor as potential treatments in IBD and cancers"
11:20	Dr. Rubartelli A.
	Proton-pump inhibitors inhibit pro-inflammatory cytokine production by monocytes/macrophages and protect mice from acute sepsis
11:40	Dr. Soveral G.
	Aquaporin therapeutic modulation: emerging targets for drug discovery
12:00	Dr. Katjar E.
	Resting potential of cancer stem cells

12:20	Opening Discussion