Lisbon
BM1406 : Ion Channels and Immune Response toward a global understanding of immune cell physiology and for new therapeutic approaches (IONCHAN-IMMUNRESPON)
WG3 Meeting
10-12th March 2016
Faculty of Pharmacy - University of Lisbon, Portugal
Agenda of Lisbon Meeting
COST Action no. BM1406
Action Title : Ion Channels and Immune Response toward a global understanding of immune cell physiology and for new therapeutic approaches (IONCHAN-IMMUNRESPON)
Lisbon, Portugal from 9th March to 11th March 2016
Wednesday 9th March
COST Action no. BM1406
Action Title : Ion Channels and Immune Response toward a global understanding of immune cell physiology and for new therapeutic approaches (IONCHAN-IMMUNRESPON)
Lisbon, Portugal from 9th March to 11th March 2016
Wednesday 9th March
14:00 - 16:00 : Registration
16:00 - 16:30 : Welcome address
16:30 - 17:30 : Opening Lecture - Dr. Pierre Martineau (Fr) - Design and use of antibody libraries for the development of therapeutic antibodies
17:30 - 18:20 : Pr. Thomas De Coursey (USA)
18:20 : Welcome drink
16:00 - 16:30 : Welcome address
16:30 - 17:30 : Opening Lecture - Dr. Pierre Martineau (Fr) - Design and use of antibody libraries for the development of therapeutic antibodies
17:30 - 18:20 : Pr. Thomas De Coursey (USA)
18:20 : Welcome drink
Thursday 10th March 2016
Lecture 1
09:00 - 10:00 : Dr. Catelijne Stortelers, Ablynx (Ge) - Therapeutic targeting of ion channels with Nanobodies.
10:00 - 10:20 : Dr. Ettrich R. - Cation translocation in human ORAI channels : Modeling and simulations.
10:20 - 10:40 : Coffee break / posters
10:40 - 11:00 : Pintro Espinoza C. - Nanobodies that antagonize the P2X7 ion channel ameliorate inflammatory diseases
11:00 - 11:20 : Dr. Rupprecht A. - A proton leak during proliferation?
11:20 - 11:40 : Dr. Louvet C. - Exploring the role of Torid cation fluxes in Th17 cells
11:40 - 12:00 : Dr. Jawhari A. - Native and functional isolation of ion channels for therapeutic purposes
12:00 - 14:00 : Lunch
Lecture 2
14:00 - 15:00 : Pr. Claude Malvy, Roussy Institute (Fr) - Therapeutic siRNAs : principle of action and cell delivery by functionalized Nanoparticles.
15:00 - 15:20 : Dr. Konu O. - Identification and validation of the mRNA-miRNA coexpression network obtained from a CHRNA5 RNAi model in MCF7 cells.
15:20 - 15:40 : Dr. Majewski L. - Transgenic mice overexpressing key store operated calcium entry proteins in neurons offer novel possibilities for studying calcium signalling in AD.
15:40 - 16:00 : Coffee break / Poster
16:00 - 16:30 : Dr. Rottoli E. - Signaling and metabolic reprogramming of effector / memory T cells by purinergic P2X7 receptor
16:30 - 18:30 : MC Meeting - H2020
20:00 : Meeting Dinner
10:00 - 10:20 : Dr. Ettrich R. - Cation translocation in human ORAI channels : Modeling and simulations.
10:20 - 10:40 : Coffee break / posters
10:40 - 11:00 : Pintro Espinoza C. - Nanobodies that antagonize the P2X7 ion channel ameliorate inflammatory diseases
11:00 - 11:20 : Dr. Rupprecht A. - A proton leak during proliferation?
11:20 - 11:40 : Dr. Louvet C. - Exploring the role of Torid cation fluxes in Th17 cells
11:40 - 12:00 : Dr. Jawhari A. - Native and functional isolation of ion channels for therapeutic purposes
12:00 - 14:00 : Lunch
Lecture 2
14:00 - 15:00 : Pr. Claude Malvy, Roussy Institute (Fr) - Therapeutic siRNAs : principle of action and cell delivery by functionalized Nanoparticles.
15:00 - 15:20 : Dr. Konu O. - Identification and validation of the mRNA-miRNA coexpression network obtained from a CHRNA5 RNAi model in MCF7 cells.
15:20 - 15:40 : Dr. Majewski L. - Transgenic mice overexpressing key store operated calcium entry proteins in neurons offer novel possibilities for studying calcium signalling in AD.
15:40 - 16:00 : Coffee break / Poster
16:00 - 16:30 : Dr. Rottoli E. - Signaling and metabolic reprogramming of effector / memory T cells by purinergic P2X7 receptor
16:30 - 18:30 : MC Meeting - H2020
20:00 : Meeting Dinner
Friday 11th March
Lecture 3
09:00 - 10:00 : Dr. Jean-François Liégois, Liège (Be) - Chemical and biological tools to explore SK channel functions and therapeutic potentials.
10:00 - 10:20 : Dr. Quieroz M.J. - Synthesis of heterocyclic compounds that may interact with ion channels producing an immune response.
10:20 - 10:40 : Dr. Martin-Sanchez F. - Novel blockers of P2X7 receptor-induced membrane permeabilization inhibit unconventional IL-1² release.
10:40 - 11:00 : Coffee break / Poster
11:00 - 11:20 : Homerin G. - "Synthesis of new ligands of the P2X7 receptor as potential treatments in IBD and cancers".
11:20 - 11:40 : Dr. Rubartelli A. - Proton-pump inhibitors inhibit pro-inflammatory cytokine production by monocytes/macrophages and protect mice from acute sepsis.
11:40 - 12:00 : Aquaporin therapeutic modulation : emerging targets for drug discovery.
12:00 - 12:20 : Dr. Katjar E. - Resting potential of cancer stem cells
12:20 : Opening Discussion