Zagreb

COST Action no. BM1406
Ruđer Bošković Institute
September 15th -16th 2016

Scientific program

Thursday 15th September

9:00 - 9:20 : Registration
9:20 - 9:30 : Welcome Address

Chair : Ruth
9:30 - 10:10 : Rainer Schindl - Transcriptional activation and open Orai1 pore structure induced by cancerous mutagenesis.
10:10 - 10:45 : Eitan Reuvny - Insights into the regulation of SOCE by SARAF
10:45 - 11:20 : Break

Chair : Florence
11:20 - 11:50 : Mariastefania Antica - Insight into immune cell development in health and leukemia.
11:50 - 12:15 : Claudia Rodrigues - Influence of oxidative stress on aquaporin expression in cancer and immune cells.
12:15 - 12:40 : Anna Rubartelli - Targeting cellular stress responses to cure tumors : old drugs are new again.
12:40 - 14:15 : Lunch

Chair : Ivana
14:15 - 14:35 : Kinda Gazda - The role of amyloid precursor protein in endoplasmic reticulum Ca2+ homeostasis.
14:35 - 14:55 - Marco Tozzi - The P2X7 receptor regulates acute glucose-stimulated ATP release, insulin secretion and β-cell proliferation.
14:55 - 15:10 : Carolina Pinto - Blocking and enhancing ATP-induced inflammasome assembly in mouse peritoneal macrophages with P2X7-specific nanobodies.
15:10 - 15:25 : Arnau Serracant-Prat - Anti-P2X7 nanobodies block ATP-induced inflammasome assembly and release of IL-1β in LPS-primed human monocytes.
15:25 - 16:30 : Break and Posters (guided tour).

Chair : Fritz
16:30 - 17:10 : Sahil Adriouch - AAVnano : a novel strategy based on AAV vectors and on selected nanobodies to knockdown and study P2X7 function in vivo.
17:10 - 17:50 : Colin Adrain - Physiological and cellular roles of iRhoms in cytokine and growth factor signaling.
 

Friday 16th September

Chair : Francesco
9:00 - 9:45 : Darek Gorecki - P2RX7 purinoceptor as a target in Duchenne muscular dystrophy treatment.
9:45 - 10:10 : Alba Clara Sarti - Modulation of mitochondrial energy metabolism by P2X7 receptor.
10:10 - 10:35 : Fabio Grassi - Extracellular ATP originated from gut colonization promotes metabolic homeostasis by controlling T follicular helper cells via P2X7 receptor.
10:40 - 11:10 : Break.

Chair : Ana
11:10 - 11:35 : Jost Ludvig - MIFE and FLISE : Alternative non invasive electrophysiological mehods to analyze ion fluxes across cell membranes.
11:35 - 11:55 : Ozlen Konu -  Extraction of an ion channel-drug network using MCF7 Connectivity Map (cMAP) dataset.
11:55 - 12:15 : Paul Buchanan - The role of voltage-gated ion channels in prostate cancer progression.
12:15 - 12:35 : Pelletier Lucette - Cav1 calcium channels in Th2 cells : therapeutic implications in allergy.
12:35 - 14:15 : Lunch
14:15 - 16:30 : Management meeting - Round table discussion

Closing remarks